Supplemental oxygen in normoxemic acute MI
Why flagged
Oxygen ordered in MI patient with O2 sat 94% (normoxemic); DETO2X-AMI 2017 showed no mortality benefit and potential harm in normoxemic patients.
Universal administration of high-flow supplemental oxygen…
No reduction in 1-year all-cause mortality (5.0% vs. 5.1%, HR 0.97, p=NS) or rehospitalization with routine oxygen in normoxemic MI patients.
Guidelines updated
ESC/ACC/AHA Guidelines (2017): Supplemental oxygen is ind…
- Prior guidance2017
Universal administration of high-flow supplemental oxygen to all patients with suspected acute myocardial infarction, regardless of baseline saturation.
- DETO2X-AMI2017
No reduction in 1-year all-cause mortality (5.0% vs. 5.1%, HR 0.97, p=NS) or rehospitalization with routine oxygen in normoxemic MI patients.
- Reversal2017
Guidelines updated
- Current recommendation
ESC/ACC/AHA Guidelines (2017): Supplemental oxygen is indicated only if the patient presents with frank hypoxemia (arterial oxygen saturation < 90%).